01.09.12+-+Membrane+&+Complex+Lipid+Metabolism


 * Membrane & Complex Lipid Metabolism**


 * 1. Be able to explain why some fatty acids are considered essential from both a metabolic and functional point of view**


 * 2. Name three enzymes of importance in eicosanoid metabolism and describe their function, cellular location, substrates, and products**


 * 3. Describe the difference between and give examples of irreversible and reversible drug inhibitors of cyclooxygenase**


 * 4. Be able to differentiate structurally between sphingolipids and glycerophospholipids. Be able to identify and name the precursors in sphingolipid and glycerophospholipid biosynthesis**


 * 5. Describe the difference between synthesis of phosphatidylcholine and phosphatidylinositol and the role of CTP in complex lipid synthesis**


 * 6. List and be able to discuss the functions of sphingolipids and glycerophospholipids. Describe the composition and proposed function of lipid rafts in membrane biology**


 * 7. Identify the significance of phospholipase A2 and phospholipase C in lipid metabolism and signaling.**


 * 8. Describe the pathophysiology of respiratory distress syndrome and how it relates to phosphoglyceride metabolism.**